APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection

APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection

An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.

Bibliographic Details
Main Authors: Ping An, Efe Sezgin, Gregory D. Kirk, Priya Duggal, Elizabeth Binns-Roemer, George Nelson, Sophie Limou, Mark L. Van Natta, Douglas A. Jabs, Michelle Estrella, Jeffrey B. Kopp, Cheryl A. Winkler
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01812-z

Internet

https://doi.org/10.1038/s42003-021-01812-z

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