APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection
An et al. determine the presence of variants of the innate immune factor APOL1 in four cohorts of HIV-positive patients. The study suggests that APOL1 might confer carriers of two variant alleles protection from HIV related opportunistic infections, especially fungal infections.
Main Authors: | Ping An, Efe Sezgin, Gregory D. Kirk, Priya Duggal, Elizabeth Binns-Roemer, George Nelson, Sophie Limou, Mark L. Van Natta, Douglas A. Jabs, Michelle Estrella, Jeffrey B. Kopp, Cheryl A. Winkler |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-01812-z |
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