White Pepper and Piperine Have Different Effects on Pharmacokinetics of Puerarin in Rats

This study attempted to explore the effects of white pepper and its major component piperine on puerarin administered to rats. Pharmacokinetic parameters of puerarin in rats were determined by oral administration (400 mg/kg) or intravenous injection (40 mg/kg) of puerarin, pretreated with or without...

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Main Authors: Yong-Zhuo Liang, Hai-Ming Chen, Zu-Qing Su, Shao-Zhen Hou, Xiao-Ying Chen, Yi-Feng Zheng, Yu-Cui Li, Ji Lin, Janis Ya-Xian Zhan, Zi-Ren Su, Lu-Di Fu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2014/796890