Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons

Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons

Auditory function is dependent on the formation of specific innervation patterns between mechanosensory hair cells (HCs) and afferent spiral ganglion neurons (SGNs). In particular, type I SGNs must precisely connect with inner HCs (IHCs) while avoiding connections with nearby outer HCs (OHCs). The f...

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Bibliographic Details
Main Authors: Thomas M Coate, Nathalie A Spita, Kaidi D Zhang, Kevin T Isgrig, Matthew W Kelley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-08-01
Series:eLife
Subjects:
axon guidance
cochlea
auditory
spiral ganglion neuron
Semaphorin
Neuropilin
Online Access:https://elifesciences.org/articles/07830

Internet

https://elifesciences.org/articles/07830

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