LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.

LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.

The Hippo pathway directs cell differentiation during organogenesis, in part by restricting proliferation. How Hippo signaling maintains a proliferation-differentiation balance in developing tissues via distinct molecular targets is only beginning to be understood. Our study makes the unexpected fin...

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Bibliographic Details
Main Authors: Caitlin M Braitsch, D Berfin Azizoglu, Yadanar Htike, Haley R Barlow, Ulrike Schnell, Christopher P Chaney, Thomas J Carroll, Ben Z Stanger, Ondine Cleaver
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000382

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https://doi.org/10.1371/journal.pbio.3000382

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