The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans

The Molecular Chaperone HSP90 Promotes Notch Signaling in the Germline of Caenorhabditis elegans

In a genetic screen to identify genes that promote GLP-1/Notch signaling in Caenorhabditis elegans germline stem cells, we found a single mutation, om40, defining a gene called ego-3. ego-3(om40) causes several defects in the soma and the germline, including paralysis during larval development, ster...

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Bibliographic Details
Main Authors: James L. Lissemore, Elyse Connors, Ying Liu, Li Qiao, Bing Yang, Mark L. Edgley, Stephane Flibotte, Jon Taylor, Vinci Au, Donald G. Moerman, Eleanor M. Maine
Format: Article
Language:English
Published: Oxford University Press 2018-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
C. elegans
HSP90
germline stem cells
Notch
GLP-1
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.300551

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http://g3journal.org/lookup/doi/10.1534/g3.118.300551

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