Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree

Variation p.R1045H in MYH7 correlated with hypertrophic cardiomyopathy in a Chinese pedigree

Abstract Background Inherited hypertrophic cardiomyopathy (HCM) is a common heart muscle disease that damages heart function and may cause the heart to suddenly stop beating. Genetic factors play an important role in HCM. Pedigree analysis is a good way to identify the genetic defects that cause dis...

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Bibliographic Details
Main Authors: Yan Zhang, Yiyi Shang, Luo Liu, Xiaoxue Ding, Haiyan Wu, Lijiang Li, Mingjie Pang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Medical Genomics
Subjects:
Pedigree analysis
Hypertrophic cardiomyopathy
MYH7
Whole-exome sequencing
Online Access:https://doi.org/10.1186/s12920-021-01046-2

Internet

https://doi.org/10.1186/s12920-021-01046-2

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