The DNA-binding protein HTa from Thermoplasma acidophilum is an archaeal histone analog

Histones are a principal constituent of chromatin in eukaryotes and fundamental to our understanding of eukaryotic gene regulation. In archaea, histones are widespread but not universal: several lineages have lost histone genes. What prompted or facilitated these losses and how archaea without histo...

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Bibliographic Details
Main Authors: Antoine Hocher, Maria Rojec, Jacob B Swadling, Alexander Esin, Tobias Warnecke
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/52542