Integrated Multiple "-omics" Data Reveal Subtypes of Hepatocellular Carcinoma.

Hepatocellular carcinoma is one of the most heterogeneous cancers, as reflected by its multiple grades and difficulty to subtype. In this study, we integrated copy number variation, DNA methylation, mRNA, and miRNA data with the developed "cluster of cluster" method and classified 256 HCC...

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Bibliographic Details
Main Authors: Gang Liu, Chuanpeng Dong, Lei Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5091875?pdf=render