Approximating attractors of Boolean networks by iterative CTL model checking

This paper introduces the notion of approximating asynchronous attractors of Boolean networks by minimal trap spaces. We define three criteria for determining the quality of an approximation: faithfulness which requires that the oscillating variables of all attractors in a trapspace correspond to th...

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Bibliographic Details
Main Authors: Hannes eKlarner, Heike eSiebert
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00130/full