Characterization of inhibitory effects of the potential therapeutic inhibitors, benzoic acid and pyridine derivatives, on the monophenolase and diphenolase activities of tyrosinase

Objective(s):Involvement of tyrosinase in the synthesis of melanin and cell signaling pathway has made it an attractive target in the search for therapeutic inhibitors for treatment of different skin hyperpigmentation disorders and melanoma cancers. Materials and Methods: In the present study, we co...

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Bibliographic Details
Main Authors: Nematollah Gheibi, Negar Taherkhani, Abolfazl Ahmadi, Kamahldin Haghbeen, Dariush Ilghari
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_4012_c70a3f67e49af12b3256c12e67466b5d.html