Evaluation of a Fully Automated Antinuclear Antibody Indirect Immunofluorescence Assay in Routine Use

Evaluation of a Fully Automated Antinuclear Antibody Indirect Immunofluorescence Assay in Routine Use

Indirect immunofluorescence assay (IFA) using HEp-2 cells as a substrate is the gold standard for detecting antinuclear antibodies (ANA) in patient serum. However, the ANA IFA has labor-intensive nature of the procedure and lacks adequate standardization. To overcome these drawbacks, the automation...

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Bibliographic Details
Main Authors: Hyun-Woo Choi, Yong Jun Kwon, Ju-Heon Park, Seung-Yeob Lee, Sejong Chun, Eun Jeong Won, Jun Hyung Lee, Hyun-Jung Choi, Soo Hyun Kim, Myung-Geun Shin, Jong-Hee Shin, Seung-Jung Kee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
antinuclear antibody
immunofluorescence assay
automation
pattern recognition
titer estimation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.607541/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.607541/full

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