Increased Frequency of T Follicular Helper Cells and Elevated Interleukin-27 Plasma Levels in Patients with Pemphigus.

Pemphigus is an autoimmune disease in which IgG auto-antibodies (auto-ab) against the desmosomal cadherins desmoglein (Dsg) 3 and Dsg1 cause loss of epidermal keratinocyte adhesion. Aim of this study was to investigate cytokines derived from antigen-presenting cells (APC) and their relation to CD4+...

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Bibliographic Details
Main Authors: Tina Hennerici, Robert Pollmann, Thomas Schmidt, Maria Seipelt, Björn Tackenberg, Christian Möbs, Kamran Ghoreschi, Michael Hertl, Rüdiger Eming
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752242?pdf=render