A Cosine Similarity-Based Method to Infer Variability of Chromatin Accessibility at the Single-Cell Level

A Cosine Similarity-Based Method to Infer Variability of Chromatin Accessibility at the Single-Cell Level

Cellular identity between generations of developing cells is propagated through the epigenome particularly via the accessible parts of the chromatin. It is now possible to measure chromatin accessibility at single-cell resolution using single-cell assay for transposase accessible chromatin (scATAC-s...

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Bibliographic Details
Main Authors: Stanley Cai, Georgios K. Georgakilas, John L. Johnson, Golnaz Vahedi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Genetics
Subjects:
single-cell
chromatin
ATAC-seq
multidimensional scaling
variation
code:R
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00319/full

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https://www.frontiersin.org/article/10.3389/fgene.2018.00319/full

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