T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

T- and NK-cell populations with regulatory phenotype and markers of apoptosis in circulating lymphocytes of patients with CIN3 or microcarcinoma of the cervix: evidence for potential mechanisms of immune suppression

Abstract Background Processes and mechanisms responsible for systemic immune suppression in early-stage cervical cancer remain substantially underinvestigated. In this work, we focused on studying the frequencies of circulating regulatory T (CD4 and CD8 Tregs) and NK (NKregs) cells in parallel with...

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Bibliographic Details
Main Authors: Olga V. Kurmyshkina, Pavel I. Kovchur, Ludmila V. Schegoleva, Tatyana O. Volkova
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Infectious Agents and Cancer
Subjects:
Immune suppression
Immunoregulatory mechanisms
Peripheral blood lymphocytes
Innate and acquired immunity
Apoptosis
Regulatory T cells
Online Access:http://link.springer.com/article/10.1186/s13027-017-0166-1

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http://link.springer.com/article/10.1186/s13027-017-0166-1

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