Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway

Targeting Glycogen Synthase Kinase 3 Beta Regulates CD47 Expression After Myocardial Infarction in Rats via the NF-κB Signaling Pathway

The aim of this study was to investigate the effects of the GSK-3β/NF-κB pathway on integrin-associated protein (CD47) expression after myocardial infarction (MI) in rats. An MI Sprague Dawley rat model was established by ligating the left anterior descending coronary artery. The rats were divided i...

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Bibliographic Details
Main Authors: Li-Na Xu, Shu-Hui Wang, Xue-Ling Su, Sumra Komal, Hong-Kun Fan, Li Xia, Li-Rong Zhang, Sheng-Na Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
glycogen synthase kinase 3 beta
integrin-associated protein
myocardial infarction
primary rat cardiomyocytes
NF-κB signaling pathway
hypoxia
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.662726/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.662726/full

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