Polychlorinated Biphenyls and Leukocyte Telomere Length: An Analysis of NHANES 1999–2002

Polychlorinated biphenyls (PCBs) induce the expression of the proto-oncogene c-myc which has a role in cellular growth and proliferation programs. The c-myc up-regulates the telomerase reverse transcriptase which adds the telomeres repeating sequences to the chromosomal ends to compensate for the pr...

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Bibliographic Details
Main Authors: Franco Scinicariello, Melanie C. Buser
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415302127