Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

Klotho ameliorates oxidized low density lipoprotein (ox-LDL)-induced oxidative stress via regulating LOX-1 and PI3K/Akt/eNOS pathways

Abstract Background Atherosclerosis is a common cardiovascular disease that causes myocardial infarction, heart failure, and stroke. Increased oxidized low density lipoprotein (ox-LDL) in the sub-endothelium is the characteristic origin of atherogenesis. Klotho, an anti-aging protein, has been repor...

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Bibliographic Details
Main Authors: Yansheng Yao, Yanbing Wang, Yibo Zhang, Chang Liu
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Lipids in Health and Disease
Subjects:
Klotho
Oxidized low density lipoprotein
Oxidative stress
Lectin-like ox-LDL receptor
Human umbilical vein endothelial cells
Online Access:http://link.springer.com/article/10.1186/s12944-017-0447-0

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http://link.springer.com/article/10.1186/s12944-017-0447-0

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