Short-Term Fever-Range Hyperthermia Accelerates NETosis and Reduces Pro-inflammatory Cytokine Secretion by Human Neutrophils

Fever is a hallmark of infections and inflammatory diseases, represented by an increase of 1–4°C in core body temperature. Fever-range hyperthermia (FRH) has been shown to increase neutrophil recruitment to local sites of infection. Here, we evaluated the impact of a short period (1 h) of FRH (STFRH...

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Main Authors: Irene A. Keitelman, Florencia Sabbione, Carolina M. Shiromizu, Constanza Giai, Federico Fuentes, David Rosso, Camila Ledo, Maximiliano Miglio Rodriguez, Mauricio Guzman, Jorge R. Geffner, Jeremías Galletti, Carolina Jancic, Marisa I. Gómez, Analía S. Trevani
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02374/full