Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

Cholesteryl ester transfer protein (CETP) transfers cholesteryl ester (CE) and triglyceride between HDL and apoB-containing lipoproteins. Anacetrapib (ANA), a reversible inhibitor of CETP, raises HDL cholesterol (HDL-C) and lowers LDL cholesterol in dyslipidemic patients; however, the effects of ANA...

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Bibliographic Details
Main Authors: Jose Castro-Perez, François Briand, Karen Gagen, Sheng-Ping Wang, Ying Chen, David G. McLaren, Vinit Shah, Rob J. Vreeken, Thomas Hankemeier, Thierry Sulpice, Thomas P. Roddy, Brian K. Hubbard, Douglas G. Johns
Format: Article
Language:English
Published: Elsevier 2011-11-01
Series:Journal of Lipid Research
Subjects:
cholesteryl ester transfer protein
cholesterol efflux
high density lipoprotein
low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520350860

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http://www.sciencedirect.com/science/article/pii/S0022227520350860

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