The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.

Activation of CD4 T cells is a reaction to challenges such as microbial pathogens, cancer and toxins that defines adaptive immune responses. The roles of T cell receptor crosslinking, intracellular signaling, and transcription factor activation are well described, but the importance of post-transcri...

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Bibliographic Details
Main Authors: Thomas C Whisenant, Eigen R Peralta, Lauren D Aarreberg, Nina J Gao, Steven R Head, Phillip Ordoukhanian, Jamie R Williamson, Daniel R Salomon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4671683?pdf=render

Internet

http://europepmc.org/articles/PMC4671683?pdf=render

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