A composition of bractatin and neobractatin from the fruits of Garcinia bracteata induces apoptosis in throat cancer through the endoplasmic reticulum stress, mitochondrial apoptotic and Akt pathways

Throat cancer is a common head and neck malignant tumor with a relatively high mortality rate. Prenylxanthone, is the major bioactive substance isolated from the genus Garcinia with anti-cancer effects. However, the anti-tumor activity of Prenylxanthone and its molecular mechanism in throat cancer h...

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Bibliographic Details
Main Authors: Huiqi Huang, Yu Peng, Tongxi Zhou, Xiandong Zhou, Jingtong Deng, Xinzhou Yang, Guangzhong Yang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Functional Foods
Subjects:
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464621002346