Comparison of statistical models to estimate parasite growth rate in the induced blood stage malaria model

Comparison of statistical models to estimate parasite growth rate in the induced blood stage malaria model

Abstract Background The efficacy of vaccines aimed at inhibiting the growth of malaria parasites in the blood can be assessed by comparing the growth rate of parasitaemia in the blood of subjects treated with a test vaccine compared to controls. In studies using induced blood stage malaria (IBSM), a...

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Bibliographic Details
Main Authors: Leesa F. Wockner, Isabell Hoffmann, Peter O’Rourke, James S. McCarthy, Louise Marquart
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Malaria Journal
Subjects:
Statistical modelling
Fixed intercept regression
Parasite growth rate
Controlled human malaria infection
Induced blood stage malaria
Clinical trial
Online Access:http://link.springer.com/article/10.1186/s12936-017-1999-1

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http://link.springer.com/article/10.1186/s12936-017-1999-1

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