The Prerequisites for Central Tolerance Induction against Citrullinated Proteins in the Mouse.

The Prerequisites for Central Tolerance Induction against Citrullinated Proteins in the Mouse.

To assess the prerequisites for negative selection of peptidylcitrulline-specific T cells in the thymus. In detail, we here analyzed murine medullary thymic epithelial cells for the expression of peptidylarginine deiminases (PAD) and subsequent citrullination.Medullary thymic epithelial cells were s...

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Bibliographic Details
Main Authors: Robby Engelmann, Andra Biemelt, Antje Cordshagen, Anja Johl, Daniela Kuthning, Brigitte Müller-Hilke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4928850?pdf=render

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http://europepmc.org/articles/PMC4928850?pdf=render

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