The neurovascular unit in diffuse intrinsic pontine gliomas

The neurovascular unit in diffuse intrinsic pontine gliomas

Aims: Diffuse intrinsic pontine glioma (DIPG) is a childhood brainstem tumor with a median overall survival of eleven months. Lack of chemotherapy efficacy may be related to an intact blood-brain barrier (BBB). In this study we aim to investigate the neurovascular unit (NVU) in DIPG patients. Me...

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Bibliographic Details
Main Authors: Fatma E. El-Khouly, Rianne Haumann, Marjolein Breur, Sophie E.M. Veldhuijzen van Zanten, Gertjan J.L. Kaspers, N. Harry Hendrikse, Esther Hulleman, Dannis G. van Vuurden, Marianna Bugiani
Format: Article
Language:English
Published: University of Münster / Open Journals System 2021-07-01
Series:Free Neuropathology
Subjects:
Diffuse intrinsic pontine glioma (DIPG)
Neurovascular unit (NVU)
Blood-brain barrier (BBB)
Tight junctions
Brainstem
Pons
Online Access:https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3341

Internet

https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3341

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