PKM2 enhances cancer invasion via ETS-1-dependent induction of matrix metalloproteinase in oral squamous cell carcinoma cells.
<h4>Objectives</h4>This study aimed at investigating the molecular mechanism underlying PKM2-mediated cancer invasion.<h4>Materials & methods</h4>To optimize the investigation of PKM2-specific effects, we used two immortalized oral cell lines. The two cell lines drastical...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0216661 |