PKM2 enhances cancer invasion via ETS-1-dependent induction of matrix metalloproteinase in oral squamous cell carcinoma cells.

PKM2 enhances cancer invasion via ETS-1-dependent induction of matrix metalloproteinase in oral squamous cell carcinoma cells.

<h4>Objectives</h4>This study aimed at investigating the molecular mechanism underlying PKM2-mediated cancer invasion.<h4>Materials & methods</h4>To optimize the investigation of PKM2-specific effects, we used two immortalized oral cell lines. The two cell lines drastical...

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Bibliographic Details
Main Authors: Young-Jin Park, Jue Young Kim, Doo Young Lee, Xianglan Zhang, Shadavlonjid Bazarsad, Won-Yoon Chung, Jin Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0216661

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https://doi.org/10.1371/journal.pone.0216661

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