Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Abstract Background The involvement of inflammasome activation and macrophage polarization during the process of syphilis infection remains unknown. In this study, A series of experiments were performed using human macrophages to research the role of NLRP3 inflammasome regulation in interleukin (IL)...

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Bibliographic Details
Main Authors: Li-Rong Lin, Wei Liu, Xiao-Zhen Zhu, Yu-Yan Chen, Zheng-Xiang Gao, Kun Gao, Man-Li Tong, Hui-Lin Zhang, Yao Xiao, Wen-Dong Li, Shu-Lian Li, Hui-Ling Lin, Li-Li Liu, Zan-Xi Fang, Jian-Jun Niu, Yong Lin, Tian-Ci Yang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Immunology
Subjects:
Treponema pallidum
Macrophage
Polarization
NLRP3
IL-1β
Online Access:http://link.springer.com/article/10.1186/s12865-018-0265-9

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http://link.springer.com/article/10.1186/s12865-018-0265-9

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