Prenatal transplantation of human amniotic fluid stem cell could improve clinical outcome of type III spinal muscular atrophy in mice

Prenatal transplantation of human amniotic fluid stem cell could improve clinical outcome of type III spinal muscular atrophy in mice

Abstract Spinal muscular atrophy (SMA) is a single gene disorder affecting motor function in uterus. Amniotic fluid is an alternative source of stem cell to ameliorate SMA. Therefore, this study aims to examine the therapeutic potential of Human amniotic fluid stem cell (hAFSC) for SMA. Our SMA mode...

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Bibliographic Details
Main Authors: Steven W. Shaw, Shao-Yu Peng, Ching-Chung Liang, Tzu-Yi Lin, Po-Jen Cheng, T’sang-T’ang Hsieh, Hao-Yu Chuang, Paolo De Coppi, Anna L. David
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88559-z

Internet

https://doi.org/10.1038/s41598-021-88559-z

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