Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation

Inhibition of NF-κB signalling has been demonstrated as a therapeutic option in treating inflammatory diseases and cancers. Herein, we synthesized novel dissymmetric 3,5-bis(arylidene)-4-piperidones (BAPs, 83–102) and characterized fully. MTT and ELISA assay were performed to screen the anti-hepatom...

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Bibliographic Details
Main Authors: Chang-Ming Su, Gui-Ge Hou, Chun-Hua Wang, Hong-Qin Zhang, Cheng Yang, Mei Liu, Yun Hou
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2019.1635124