Development of a Curcumin-Loaded Polymeric Microparticulate Oral Drug Delivery System for Colon Targeting by Quality-by-Design Approach

Development of a Curcumin-Loaded Polymeric Microparticulate Oral Drug Delivery System for Colon Targeting by Quality-by-Design Approach

The purpose of this study was to apply the quality-by-design (QbD) approach for the development of colon-targeted curcumin-loaded polymeric microparticles (Col-CUR-MPs). The proportion of the enterosoluble polymer (Eudragit<sup>®</sup> FS) in the polymeric matrix, curcumin concentration,...

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Bibliographic Details
Main Authors: Dana Hales, Lucia Ruxandra Tefas, Ioan Tomuță, Cristian Moldovan, Diana Gulei, Raluca Munteanu, Alina Porfire
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
curcumin
Eudragit® FS
polycaprolactone
microspheres
colon-specific delivery
quality-by-design
Online Access:https://www.mdpi.com/1999-4923/12/11/1027

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https://www.mdpi.com/1999-4923/12/11/1027

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