Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer

Discovery of Molecular DNA Methylation-Based Biomarkers through Genome-Wide Analysis of Response Patterns to BCG for Bladder Cancer

Background: Bacillus Calmette-Guérin (BCG) immunotherapy, the standard adjuvant intravesical therapy for some intermediate and most high-risk non-muscle invasive bladder cancers (NMIBCs), suffers from a heterogenous response rate. Molecular markers to help guide responses are scarce and currently no...

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Bibliographic Details
Main Authors: Dafina Ilijazi, Walter Pulverer, Iris E. Ertl, Ursula Lemberger, Shoji Kimura, Mohammad Abufaraj, David D’Andrea, Benjamin Pradere, Andreas Bruchbacher, Anna Graf, Francesco Soria, Martin Susani, Andrea Haitel, Luca Molinaro, Armin Pycha, Evi Comploj, Stephan Pabinger, Andreas Weinhäusel, Gerda Egger, Shahrokh F. Shariat, Melanie R. Hassler
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cells
Subjects:
bladder cancer
Bacillus Calmette-Guérin
DNA methylation marker
urothelial cancer
Illumina MethylationEPIC BeadChip
high-risk bladder cancer
Online Access:https://www.mdpi.com/2073-4409/9/8/1839

Internet

https://www.mdpi.com/2073-4409/9/8/1839

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