Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors—A Possible Involvement of DC-STAMP

It is well established that multinucleation is central for osteoclastic bone resorption. However, our knowledge on the mechanisms regulating how many nuclei an osteoclast will have is limited. The objective of this study was to investigate donor-related variations in the fusion potential of in vitro...

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Bibliographic Details
Main Authors: Anaïs M. J. Møller, Jean-Marie Delaissé, Jacob B. Olesen, Luisa M. Canto, Silvia R. Rogatto, Jonna S. Madsen, Kent Søe
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
CTX
Online Access:https://www.mdpi.com/1422-0067/21/17/6368