Microvascularized tumor organoids-on-chips: advancing preclinical drug screening with pathophysiological relevance

Abstract Recent developments of organoids engineering and organ-on-a-chip microfluidic technologies have enabled the recapitulation of the major functions and architectures of microscale human tissue, including tumor pathophysiology. Nevertheless, there remain challenges in recapitulating the comple...

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Bibliographic Details
Main Authors: Jungeun Lim, Hanna Ching, Jeong-Kee Yoon, Noo Li Jeon, YongTae Kim
Format: Article
Language:English
Published: SpringerOpen 2021-04-01
Series:Nano Convergence
Subjects:
Online Access:https://doi.org/10.1186/s40580-021-00261-y