MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors.

MAK33 antibody light chain amyloid fibrils are similar to oligomeric precursors.

Little structural information is available so far on amyloid fibrils consisting of immunoglobulin light chains. It is not understood which features of the primary sequence of the protein result in fibril formation. We report here MAS solid-state NMR studies to identify the structured core of κ-type...

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Bibliographic Details
Main Authors: Manuel Hora, Riddhiman Sarkar, Vanessa Morris, Kai Xue, Elke Prade, Emma Harding, Johannes Buchner, Bernd Reif
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5528828?pdf=render

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http://europepmc.org/articles/PMC5528828?pdf=render

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