Targeting Nrf2 for the treatment of Duchenne Muscular Dystrophy

Targeting Nrf2 for the treatment of Duchenne Muscular Dystrophy

Imbalances in redox homeostasis can result in oxidative stress, which is implicated in various pathological conditions including the fatal neuromuscular disease Duchenne Muscular Dystrophy (DMD). DMD is a complicated disease, with many druggable targets at the cellular and molecular level including...

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Bibliographic Details
Main Authors: Stephanie Kourakis, Cara A. Timpani, Judy B. de Haan, Nuri Gueven, Dirk Fischer, Emma Rybalka
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
Nrf2
Reactive oxygen species
Oxidative stress
Skeletal muscle
Hormesis
Duchenne muscular dystrophy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720310089

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http://www.sciencedirect.com/science/article/pii/S2213231720310089

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