The Dynamics of Dendritic Cell—Mediated Innate Immune Regulation

After taking up pathogen-derived antigens, dendritic cells (DCs) leave peripheral organs and migrate into sentinel lymph nodes via afferent lymphatic vessels. During this process, they undergo maturation and produce proinflammatory cytokines, which leads to efficient antigen (Ag) presentation and ac...

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Bibliographic Details
Main Author: Toshiaki Ohteki
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Allergology International
Subjects:
pDC
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015308674