Lifespan-Associated Gene Expression Signatures of Recombinant BXD Mice Implicates Coro7 and Set in Longevity

Although genetic approaches have identified key genes and pathways that promote longevity, systems-level approaches are less utilized. Here, we took advantage of the wealth of omics data characterizing the BXD family of mice. We associated transcript and peptide levels across five tissues from both...

Full description

Bibliographic Details
Main Authors: David Vitiello, Alexander Dakhovnik, Cyril Statzer, Collin Y. Ewald
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
SET
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.694033/full