White matter hyperintensities classified according to intensity and spatial location reveal specific associations with cognitive performance

White matter hyperintensities (WMHs) on T2-weighted images are radiological signs of cerebral small vessel disease. As their total volume is variably associated with cognition, a new approach that integrates multiple radiological criteria is warranted. Location may matter, as periventricular WMHs ha...

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Bibliographic Details
Main Authors: Luca Melazzini, Clare E. Mackay, Valentina Bordin, Sana Suri, Enikő Zsoldos, Nicola Filippini, Abda Mahmood, Vaanathi Sundaresan, Marina Codari, Eugene Duff, Archana Singh-Manoux, Mika Kivimäki, Klaus P. Ebmeier, Mark Jenkinson, Francesco Sardanelli, Ludovica Griffanti
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213158221000607