TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation

<p>Abstract</p> <p>Introduction</p> <p>Signaling downstream of Ras is mediated by three major pathways, Raf/ERK, phosphatidylinositol 3 kinase (PI3K), and Ral guanine nucleotide exchange factor (RalGEF). Ras signal transduction pathways play an important role in breast...

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Bibliographic Details
Main Authors: Ward Yvona, Yin Juan, Zhao Liu, Beberman Stacey J, Oberst Michael D, Kelly Kathleen
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/189