Thrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM Patients

Thrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM Patients

It is generally known that heat shock protein 27 (HSP27) is phosphorylated through p38 mitogen-activated protein (MAP) kinase. We have previously reported that HSP27 is released from human platelets associated with collagen-induced phosphorylation. In the present study, we conducted an investigation...

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Bibliographic Details
Main Authors: Haruhiko Tokuda, Gen Kuroyanagi, Masanori Tsujimoto, Rie Matsushima-Nishiwaki, Shigeru Akamatsu, Yukiko Enomoto, Hiroki Iida, Takanobu Otsuka, Shinji Ogura, Toru Iwama, Kumi Kojima, Osamu Kozawa
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:International Journal of Molecular Sciences
Subjects:
thrombin-activating protein
HSP27
Akt
platelet
diabetes mellitus
Online Access:http://www.mdpi.com/1422-0067/17/5/737

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http://www.mdpi.com/1422-0067/17/5/737

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