Establishment of primary human breast cancer cell lines using “pulsed hypoxia” method and development of metastatic tumor model in immunodeficient mice

Establishment of primary human breast cancer cell lines using “pulsed hypoxia” method and development of metastatic tumor model in immunodeficient mice

Abstract Background Among breast cancer (BC) patients the outcomes of anticancer therapy vary dramatically due to the highly heterogeneous molecular characteristics of BC. Therefore, an extended panel of BC cell lines are required for in vitro and in vivo studies to find out new characteristic of ca...

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Bibliographic Details
Main Authors: Anna A. Nushtaeva, Anastasia A. Karpushina, Mikhail S. Ermakov, Ludmila F. Gulyaeva, Alexey V. Gerasimov, Sergey V. Sidorov, Tatyana A. Gayner, Anastasia Y. Yunusova, Anastasia V. Tkachenko, Vladimir A. Richter, Olga A. Koval
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cancer Cell International
Subjects:
Breast cancer
Primary cultures
EMT
MET
Pulsed hypoxia
E-cadherine
Online Access:http://link.springer.com/article/10.1186/s12935-019-0766-5

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http://link.springer.com/article/10.1186/s12935-019-0766-5

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