Obtaining hepatocytes by transdifferentiation of multipotent mesenchymal stromal cells by genetic engineering

Therapy of liver failure is a common and insufficiently resolved problem. One of the options for its solution it is a liver transplantation. However, this method has a number of drawbacks, which include a limited number of donors and transplant rejection. The use of autologous hepatocytes would allo...

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Bibliographic Details
Main Authors: Makeyev Oleg, Korotkov Arteom, Kostyukova Svetlana, Shuman Evgeny, Desyatova Mariya
Format: Article
Language:English
Published: EDP Sciences 2020-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/full_html/2020/06/bioconf_icli2020_02015/bioconf_icli2020_02015.html