LincRNA Plays a Role in the Effect of CYP46A1 Polymorphism in Alzheimer’s Disease – Related Pathology
Polymorphism of the cholesterol-24S-hydroxylase (CYP46A1) gene is thought to be a risk factor for Alzheimer’s disease (AD). A single nucleotide polymorphism (T/C) in intron 2, rs754203, has been confirmed to be implicated in AD. Rs754203 is located in the long intronic non-coding RNA (LincRNA) seque...
Main Authors: | Yang Chen, Hui-Yun Li, Fan Zeng, Le Chen, Fa-Ying Zhou, Ze-Yan Peng, Hai Yang, Hua-Dong Zhou, Yan-Jiang Wang, Ling Li |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-01-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnagi.2019.00381/full |
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