The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256.

With the HIV-1 epidemic in southern Africa still rising, a prophylactic vaccine against the region's most prolific subtype (subtype C) would be a significant step forward. In this paper we report on the effect of 2 different adjuvants, AddaVax and AlhydroGel, formulated with HIV-1 subtype C gp1...

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Bibliographic Details
Main Authors: Michiel T van Diepen, Rosamund Chapman, Penny L Moore, Emmanuel Margolin, Tandile Hermanus, Lynn Morris, Phindile Ximba, Edward P Rybicki, Anna-Lise Williamson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208310