Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole Clustering
A major limitation of clinically used cancer drugs is the lack of specificity resulting in toxicity. To address this, we performed a phenotypically-driven screen to identify optimal multidrug combinations acting with high efficacy and selectivity in clear cell renal cell carcinoma (ccRCC). The searc...
Main Authors: | Andrea Weiss, Morgan Le Roux-Bourdieu, Marloes Zoetemelk, George M. Ramzy, Magdalena Rausch, Daniela Harry, Marijana Miljkovic-Licina, Katayoun Falamaki, Bernard Wehrle-Haller, Patrick Meraldi, Patrycja Nowak-Sliwinska |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/10/1612 |
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