Homozygosity disequilibrium associated with treatment response and its methylation regulation

Abstract Homozygosity disequilibrium (HD), indicating a nonrandom pattern of sizable runs of homozygosity that deviates from a random allocation of homozygous and heterozygous genotypes in the genome, is an important phenomenon in population genomics and medical genomics. We performed the first geno...

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Bibliographic Details
Main Authors: Hsin-Chou Yang, Chia-Wei Chen
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Proceedings
Online Access:http://link.springer.com/article/10.1186/s12919-018-0150-9