A comparison of approaches for combining predictive markers for personalised treatment recommendations

Abstract Background In the presence of heterogeneous treatment effects, it is desirable to divide patients into subgroups based on their expected response to treatment. This is formalised via a personalised treatment recommendation: an algorithm that uses biomarker measurements to select treatments....

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Bibliographic Details
Main Authors: Matthias Pierce, Richard Emsley
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-020-04901-2