Trypanosoma cruzi entrance through systemic or mucosal infection sites differentially modulates regional immune response following acute infection in mice.

Trypanosoma cruzi entrance through systemic or mucosal infection sites differentially modulates regional immune response following acute infection in mice.

Acute Chagas disease is characterized by a systemic infection that leads to strong activation of the adaptive immune response. Outbreaks of oral contamination by the infective protozoan Trypanosoma cruzi are frequent in Brazil and other Latin American countries, and an increased severity of clinical...

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Bibliographic Details
Main Authors: Juliana ede Meis, Juliana Barreto de Albuquerque, Danielle Silva dos Santos, Désio Aurélio Farias-de-Oliveira, Luiz Ricardo Berbert, Vinícius eCotta-de-Almeida, Wilson eSavino
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Immunology
Subjects:
Lymph Nodes
Spleen
Trypanosoma cruzi
T cell activation
Peyer´s patches
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00216/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00216/full

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