Decreased expression of the β2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

Decreased expression of the β2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

Abstract Background Lymphocyte Function-Associated Antigen-1 (LFA-1; CD18/CD11a) is one of the main adhesion molecules used by immune cells to infiltrate the liver under inflammatory conditions. Recently, the expression of this integrin has also been reported on several solid tumors, including color...

Full description

Bibliographic Details
Main Authors: Aitor Benedicto, Joana Marquez, Alba Herrero, Elvira Olaso, Elzbieta Kolaczkowska, Beatriz Arteta
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
Liver metastasis
Colorectal cancer
β2 integrin
LFA-1
ICAM-1
Immune response
Online Access:http://link.springer.com/article/10.1186/s12885-017-3823-2

Internet

http://link.springer.com/article/10.1186/s12885-017-3823-2

Similar Items