The Replacement of five Consecutive Amino Acids in the Cyt1A Protein of Bacillus thuringiensis Enhances its Cytotoxic Activity against Lung Epithelial Cancer Cells

Cyt1A protein is a cytolytic protein encoded by the cyt gene of Bacillus thuringiensis subsp. israelensis (Bti) as part of the parasporal crystal proteins produced during the sporulation. Cyt1A protein is unique compared to the other endotoxins present in these parasporal crystals. Unlike δ-endotoxi...

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Bibliographic Details
Main Authors: Kavita Nair, Ahmad Iskandarani, Roda Al-Thani, Ramzi Mohammad, Samir Jaoua
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/10/3/125